Detection of HBV by PCR in HBsAg negative people
JIA Qiu-long
ZHAO Zhi-feng
HOU Liang-bao
Abstract：Objective To observe the clinical value of detection of hepatitis B virus(HBV) by polymerase chain reaction (PCR) in HBsAg negative people. Methods Object of the study was H BsAg negative people. The HBsAg,Anti-HBe,HBeAg, Anti-HBe,Anti-HBc and Anti-HBc IgM were detected by enzyme-linked immunoabsor-bent assay. The HBV was detected by PCR. Results Among two hundred and eighty-two HBsAg negative patients, positive rate of serum HBV was 9.2%. Twenty-four cases of them had a high level of alanine aminotransferase, 16 cases had a high total bilirubin, and prothrombin time activity in 11 cases was less than 70%. Conclusion HBV could exist in blood in any model of hepatitis B markers and needs validation test. PCR is the most useful method for definitive detection of HBV.
Keywords：Hepatitis BModel of negative HBsAgPolvmerase chain reaction
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 676-677 )