Clinical observation of 78 patients with liver cirrhosis ascites treated with normal diet or natrium limited diet

LUO Zhi-gang; LAI Wei; YU Hong; ZHANG Hong-yu; ZHAO Bin

doi:10.3760/cma.j.issn.1673-4777.2009.09.015

Abstract：Objective To discuss the effect of normal diet on aseites disappearance and the complication reduction rate on liver cirrhosis ascites. Methods Seventy-eight patients suffering liver cirrhosis ascites from March 2002 to July 2006 were randomly divided into treatment group (n = 41)and control group (n = 37 ). Both groups were given routine treatment, such as protection liver, diuretics and supplement of human albumin. Besides normal diet, the treatment group was also treated by intravenous drip of hyperosmotic sodium chloride solution when patients were accompanied with hyponatremia (serum sodium < 125 mmol/L). The control group was given sodium limited diet without complement of hyperosmotic sodium chloride solution. Ascites disappearance as well as change of renal functions and electrolyte were compared before and after treatment. Results There were 28 cases of ascites disap-pearance in treatment group (68.2%) and 13 in control group (35.1%)(X = 7.83, P < 0.01 ). The average days of ascites disappearance were (9.38 ±2.75)days in normal diet group and (11.79 ±2.19) days in control group respectively. There is no patients with renal dysfunction in the normal diet group and 6 patients suffering renal dysfunction in the control group (P <0.05). No hyponatremia in the normal diet group and 18 in the control group (P < 0.05 ). Conclusion Normal diet and necessary complement of hyperosmotic sodium chloride solution and the rational use of diuretics in patients with liver cirrhosis ascites can reduce the incidence of hyponatremia and renal dysfunction, contributing to the ascites disappearance and the improvement of patient prognosis.