Correlation between C-reactive protein and coronary heart disease
CHU Qing-lian
Abstract:Objective To explore the correlation between inflammation and acute coronary syndrome (ACS), stable angina pectoris(SAP) and to investigate characteristics of cardiovascular events in acute myocardial infarction (AMI)via detecting C-reactive protein(CRP). Methods One hundred and twenty-four cases were divid-ed into AMI group (28 patients) and UAP group (35 patients). There were 33 cases in SAP group and 28 cases in normal control group. CRP concentration (mg/L) was determined by immune transmission turbidity. Results CRP significantly increased in AMI and UAP group compared with normal control group. CRP was higher in AMI group than in UAP group, SAP group and control group. CRP in UAP group was higher than in SAP group and normal control group. Compared with control group, CRP in SAP group did not significantly increase. CRP peak occurred at 48 hours after AMI. CRP in AMI (cardiovascular events) subgroup was higher than in AMI (no cardiovascular) subgroup. Conclusion Significant elevation of CRP suggests that inflammation occurs in ACS courses and reflects certain degree of myocardial injury and necroses. Significant increase of CRP can predict cardiovascular events in AMI.
Keywords:Acute coronary syndromeAngina pectorisC-reactive proteinMyocardial infarction
Publication Date:2009-01-01
Online Publishing Date:2026-09-14(First online date of this platform, not the publication date of the document)
Pages:2( 659-660 )
