Expression of CD105 in papillary thyroid carcinoma tissues
GONG You-fang
JIANG Wei-xing
ZHAO Xian-bin
ZHANG Hao
ZHANG Hai-lin
Abstract：Objective To observe the expression of CD105 in papillary thyroid carcinoma tissues(PTC). Methods The expression of endnglin (CD105) was detected by immuneohistochemical staining(SP) in 60 cases of paraffin-embedded tissue blocks. 50 cases of normal thyroid tissue and benign thyroid tumor tissue(NTBT) were en-rolled as a control group. Results NTBT didn't detect the expression of CD105. 41 of 60 cases showed a positive expression in PTC group. Among them, 34 of 39 cases showed lymphatic metastasis. Conclision The expressions of CD105 can not be detected in NTBT. PTC showed an over expression of CDI05. Increase of MVD marked by CD105 indicates a bad prognosis and PTC invasion. CD105 may be a good tumor marker in detecting potential me-tastasis in PTC.
Keywords：Papillary thyroid carcinomaLymphatic metastasisMicrovessel densityImmunohisoch-emistry
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 536-537 )