Artificial liver support system in treatment of viral hepatitis gravis
WANG Zheng-rong
Abstract：Objective To study the efficacy and safety of artificial liver support system(ALSS) in the treat-ment of hepatitis gravis. Methods Sixty-nine patients suffering from hepatitis gravis were treated with internal com-bined therapy as well as ALSS. Clinical manifestation and laboratory examination index were examined before and af-ter ALSS therapy. Moreover, the efficacy of ALSS treatment in the different stages of hepatitis gravis was investiga-ted. Results There was significant decrease of endotoxin concentration and NO level after therapy of ALSS, while PTA and ALB increased. The response rates of hepatitis gravis in early stage, middle stage and late stage were 70. 8%, 38.9% and 0 respectively. Conclusion The ALSS is effective in treating hepatitis gravis, especially in acute hepatitis gravis and in early and middle stages of chronic hepatitis gravis patients It can decrease TNF-α,endotoxin concentration and NO level and relieve liver cell injury of hepatitis gravis and improve survival rate.
Keywords：Hepatitis gravisArtificial liver support systemLiver functionEndotoxin
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 275-277 )