Relationship of serum leptin, VEGF and lung cancer
DONG Ji-hua
ZHAO Yan-ping
MA Ji-yong
Abstract：Objective To investigate the relationship of serum leptin concentration, vascular endothelial growth factor(VEGF) and lung carcinoma. Methods Blood samples were collected from 64 patients with lung cancer and 30 patients with lung benign disease were selected from the People's hospital of Heze peony district and 70 healthy people were enrolled as a control group. Serum leptin was measured by radioimmunoassay(RIA) and serum VEGF were measured by ELISA. Results The serum leptin concentration and VEGF in lung cancer group were sig-nificantly higher than in the lung benign disease and healthy control. There was no significant difference of the serum leptin between in the lung benign disease and healthy control( P>0.05 ). Conclusion Our results suggests that increased serum leptin levels may be the risk factor for lung cancer.
Keywords：Lung cancerLeptinVascular endothelial growth factor
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 258-259 )