Clinical analysis of change of serum inflammatory factors in patients with post-operative nonunion
LUO Qun-qiang
PENG Wei-bo
LUO Zhang-wei
MO Xiong-ge
HUANG Hui
Abstract：Objective To observe the relationship of changes of serium inflammatory factors in patients with post-operative nonunion. Methods Levels of tumor necrosis factor-α (TNF-α), soluble intercellular adhesion molecule-1 (sVCAM-1), and interleukin-1 (IL-1β) in 32 cases in nonunion group, in 32 healthy people(control group), and in 36 cases with fracture primary healing after operation(first intention group) were detected. Results TNF-α, sVCAM-1, IL-1β in Group 1 were higher than those in control group and first intention group (P <0.05). Conclusion Damage of endothelial function, activation of macrophage in patients with post-operative nonunion of bone fracture cause cytokines release and hinder post-operative nonunion of bone fracture.
Keywords：Post-operative nonunion of bone fractureInterlenkin-1Tumor necrosis factor-αSoluble intercellular adhesion molecule-1
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 132-133 )