Relationship between helicobacter pylori infection and serum gastrin in duodenal ulcer
LUO Xiong
XIA YuXin
YANG GuoLiang
WANG Ying
HU Qinfang
Abstract：Objective To observe the fasting serum gastrin(GAS)level in patient with duodenal ulcer which includes helicobacter pylori(Hp)positive group and Hp negative group.Methods GAS was detected with radioimmunoassay(RIA),and Hp infection was detected with rapid urease test(RUT)and Giemsa stainning in 54 patients.Repeated test was done in Hp still positive cases after one-month antibiotic therapy.Results The serum GAS level in Hp positive patients(158.51±65.48pg/ml)was higher than that in the negative(81.58±18.36)pg/ml patients(P＜0.05).After one-month antibiotic therapy,the GAS level of Hp positive patients(128.06±45.17)pg/ml was higher than patients whose Hp turned negative(76.82±16.09)pg/ml(P＜0.05).Conclusion Hp is the main causative factor in most DU cases.High gastfin caused by Hp infection producing more gastric acid may be one of the pathogeneses of Hp infection.
Keywords：Duodenal ulcerHelicobacter pyloriGastrin
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 44-45 )