Effects of thyroxine on gonad endocrine function in rats
KANG Bai
HAN Huirong
WANG Jinhong
LI Shuwei
Abstract：Objective To study the effects of thyroxine(T4)on pituitary-ovary axis in rats and its mechanism.Methods The serum LH,FSH,E2,P,IL-1βand TNF concentration was measured with radioimmunoassayE2、P concentration while increased serum IL-1βconcentration significantly in rats(P＜0.01).Conclusion T4 had an inhibiting effect on endocrine function of pituitary-ovary axis in rats by large dose T4 and using for long time.The mechanism is related to the increasing of IL-1 secretion in rats.
Keywords：EndocrineThyroxineGonad
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 12-13 )