The clinical observation and evaluation on paclitaxel liposome for injection with interventional therapy in the malignant tumor
XU You-qi
ZHANG Yu
XU Jian-wei
Abstract：Objective To observe the clinical efficacy and toxicity of Paclitaxel Liposome for Injection with interventional therapy in treatment of the malignant tumor,furthermore.the clinical effects and the degree of safety of the drugs were evaluated.Methods Thirty-two patients with malignant tumor were all treated with the interventional therapy which adopted the Seldinger techniques by femoral artery puncture and the treating vessel were intubuted to the target artery of tumor,then 90 mg of paelitaxel liposome for injection were poured into through the vessel.meanwhile the lung cancer and the pelvic tumor poured into 60mg cisplatin.the liver cancer and metastatic liver cancer poured into 1000 mg 5-fluorouracil.And a part of the liver cancer and metastatic liver cancer be treated artery embolization.Results The total effective rate(immediate effective rate)Was 50.0%after the treatment with interventional therapy in the whole 32 patients.and the toxicity Was not serious.the time in hospital of the patient Was shorter.Conclusion It was found that the immediate effective rate was fine.the toxicity was slight.and the ability of endure the suffering was good.It wag effective and secure in adopting the drugs in this treatment.So it can be application and dissemination.
Keywords：Malignant tumorPaclitaxel liposome for injection
Publication Date：2008-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 786-787 )