Efficacy and safety of telmisartan in patients with mild to moderate essential hypertension
WANG Yi
JIANG Lei
Abstract：Objective To observe the efficacy and safety of telmisartan in patients of essential hypertension.Methods This study was a randomized,double-blind and parallel controlled trial.66 eligible mild and moderate hypertension patients were divided randomly into telmisartan group and perindopril group.80mg of telmisartan or 4mg of perindopril was administrated once per day,and the patients were followed up in every two weeks.This trial was continued for 8 weeks.Results After 8 weeks,the effectiveness of telmisartan and perindopril were 72.7% and 68.8%respectively,showing no significant difference between both groups.After 8 weeks,the SBP and DBP of telmisartan group decreased 11.4%and 12.3%.perindopril group decreased 8.9%and 11.1%.Also no significant difference Was observed.The side effect ratio Was significantly lower in telmisartan group(3.2%)than that in perindopril group(15.2%).The most common side effects were COUgh and mild dizziness.Conclusion Telmisartan (80 mg/d)is effective、safe and well tolerated in treatment of mild to moderate essential hypertension.
Keywords：HypertensionTelmisartanPerindopril
Publication Date：2008-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 755-756 )