Therapeutic effect of gabapentin and oxycontin for postherpetic neuralgia
ZHANG Wei-shi
XU Ping-bo
LIU Rui-quan
XU Hua
XIONG Yuan-chang
DENG Xiao-ming
Abstract：Objective To observe the efficacy of gabapentin and oxycontin in postherpetic neuralgia. Methods ninety-eight patients with postherpetic neuralgia (PNN) were randomly allocated to the following 3 groups : group gabapentin group (n=34) ;oxycontin group (n=31) and combination group (n=WK33). The degree of pain and quality of sleep were assessed by a blinded observer using Visual Analogue Scale (VAS) and Quality of Sleep (QS) on the 1st, 3rd, 7th, 14th,28thday after therapy respectively. Results The VAS scores and QS scores of all patients decreased significantly after therapy (P<0.05). Compared with gabapentin group and oxycontin group, the VAS scores and QS scores also reduced markedly in gabapentin plus lxycontin group (P<0.01). The obvious effective rate was 88.9% and the effective rate is 100% in gabapentin plus oxycontin group. Conclusion The combined application of gabapentin and oxyeontin relieves the degree of postherpetic neuralgia and improves the quality of sleep.
Keywords：Postherpetic neuralgiaGabapentinOxyeontin
Publication Date：2008-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 602-604 )