Assess the role of actovegin in treating diabetic peripheral polyneuropathy
LU Hong-yun
SUN Liao
YE Li-hong
SHU Xiao-chun
SHEN Jing
XIE Dan-hong
Abstract：Objective To assess the role of actovegin(Deproteinized Hemoderivatire of Calf)in treating diabetic peripheral polyneuropathy.Methods One handred and fifty cases of diabetic peripheral polyneuropathy patients were divided into three groups randomly:actovegin treating group,mecobalamine treating group,actovegin and mecobalamine combination treating group.After two weeks treatment,compared the clinical symptoms and electromyogram improvements.Results Clinical symptoms and nerves conduction velocity were significantly improved after treatment.The total effective rate was 66%,70%,90%in mecobalamine treating group,actovegin treating group,actovegin and mecobalamine treating group respectively.There Was no significant difference between actovegin and mecobalamine treating group(x2=0.186,P＞0.05),but actovegin and mecobalamine combination treating group had get more benefit(90%vs 66%,x2=8.791,P＜0.05;90% vs 70%,x2=6.60,P＜0.05).Conclusion Actovegin can significant improve the clinical symptom and nerves conduction velocity.Patients get more benefit from combination of actovegin and mecobalamin
Keywords：Diabetic peripheral polyneuropathyActoveginMecobalamin
Publication Date：2008-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 536-537 )