Brain and myocardial dsmage in infant with TOF undergoing open heart surgery
CHEN Li-hua
LI Qian
LIU Lin-li
Abstract：Objective To investigate brain and myocardial danlage in infant with TOF undergoing open heart surgery.Methods Sixty patients with TOF underwent open heart surgery were randomly divided into 2 groups:aortic clamp time≤45rain group and＞45min group.Cardiac electrophysiologic data and inotropic medicine were recorded.Meanwhile serum S-10013,NSE and cTnI before cardiopulmonary bypass,30 min after aortic declamping,12 hours after operation,respectively.Results In aortic clamp time＞45min group,patients Were younger with lower body weight and EF.Heartbeat restoration time is longer,together with higher inotropic medicine dosage,and CK-MB,cTnI,S-1006,NSE at 30 min and 12 hour after aortic declamping.Aortic clamp time was negatively correlated with age,body weight and EF,and positively correlated with heartbeat restoration time,inotropic medicine dosage,CK-MB,cTnI,S-100β,NSE at 30 min and 12 hour after aortic declamping.With adjusted age,body weight and EF,the time of aorta lamp Was positively correlated with inotropic medicine dosage,cTnI,S-100β,NSE at 30 min and 12 hour after aortic declamping.Conclusion Heavy pathogenetic condition and longer time of aorta lamp caused brain and myocardial damag.
Keywords：Brain damageMyocardial damageAdenosine infantOpen heart surgery
Publication Date：2008-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 516-518 )