Diagnostic value of systemic immune inflammation index and neutrophil to lymphocyte ratio in prostate cancer
ZHANG Qingsong
ZHANG Wanze
WANG Xin
QI Jinchun
XUE Wenyong
ZHANG Ming
MENG Qingsong
YAN Bowen
WANG Yaxuan
WANG Dongbin
Abstract：Objective To explore the application value of systemic immune inflammation index(SII)and neutrophil to lymphocyte ratio(NLR)in the diagnosis of prostate cancer.Methods The clinical data of 183 patients received first ultra-sound-guided transperineal prostate biopsies from November 2021 to March 2023 were retrospectively analyzed.The patients were divided into prostate cancer group and non-prostate cancer group according to the pathological results.Multivariate Logistic re-gression analysis was used to determine the independent risk factors for the incidence of prostate cancer.And the receiver operat-ing characteristic(ROC)curve was plotted to analyze the diagnostic performance of each independent risk factor and the new prediction model in prostate cancer.The positive rates of prostate biopsy at different levels of SII,NLR and PSA were compared.Results The age,and the levels of SII,PSA,NLR,platelet to lymphocyte ratio(PLR)and lymphocyte to monocyte ratio(LMR)were significantly higher than those in the non-prostate cancer group.SII,NLR,PLR and PSA all had high diagnostic efficacy for prostate cancer.The combination of SII,NLR,PLR and PSA had the better diagnostic efficacy for prostate cancer compared to single test index.Conclusion SII and NLR are of great significance in the clinical diagnosis of prostate cancer.The combined detection of SII,NLR,PLR and PSA can improve the detection rate for prostate cancer.
Keywords：prostate cancersystemic immune inflammation indexneutrophil to lymphocyte ratiodiagnosis
Publication Date：2026-02-20
Online Publishing Date：2026-03-27(First online date of this platform, not the publication date of the document)
Pages：4( 129-132 )