Ferroptosis in the testis:Progress in research
ZHANG Wen-xiu
SUN Da-lin
JIN Bao-fang
Abstract：Ferroptosis is a form of cell death resulting from the disruption of iron metabolism within cells and excessive accumu-lation of lipid peroxides.Research indicates that,under the influence of various pathogenic factors,ferroptosis impacts the male repro-ductive system and fertility by affecting the synthesis of testicular hormones and regulation of cellular functions through different path-ways and numerators.This paper provides an overview of the action mechanisms of ferroptosis in the testis and its correlation with path-ogenicity,offering some new insights into the treatment of male reproductive system diseases.
Keywords：ferroptosistestiscell deathoxidative stresshigh-risk factors
Publication Date：2024-07-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 663-667 )