Efficacy of Lamiophlomis Rotata Capsule in the treatment of type ⅢB prostatitis
WEI Zhi-feng
ZHOU Kai
DONG Jie
FU Dian
XU Xiao-feng
LI Ping
CHENG Wen
ZHANG Zheng-yu
Abstract：Objective:To study the therapeutic effect of Lamiophlomis Rotata Capsule (LRC) in the treatment of type Ⅲ B prostatitis.Methods:We randomly divided 225 patients with type Ⅲ B prostatitis into an experimental group (n =125) and a control group (n =120),the former treated orally with LRC at 3 capsules tid while the latter with tamsulosin hydrochloride sustained-release capsules at 0.2 mg qd,both for 4 weeks.We compared the therapeutic effects between the two groups of patients based on the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) obtained before,immediately after and at 4 weeks after medication.Results:A total of 120 patients completed the treatment in the experimental group,which showed remarkable decreases as compared with the baseline in the pain score (5.30 ± 1.23 vs 14.68 ± 1.51,P ＜ 0.05),quality of life (QoL) score (6.46 ± 0.93 vs 8.52 ± 1.05,P＜0.05) and total NIH-CPSI score (17.50 ± 2.77 vs 27.99 ± 2.98,P＜0.05) after 4 weeks of treatment,but no significant change in the urination symptoms score (7.41 ± 1.16 vs 7.16 ± 1.04,P ＞ 0.05).The experimental group achieved even markedly lower scores than the controls in the pain symptom (5.30 ± 1.23 vs 13.67 ± 1.49,P ＜ 0.05),QoL (6.46 ± 0.93 vs 7.47 ± 0.88,P ＜ 0.05) and total NIH-CPSI (17.50 ± 2.77 vs 25.77 ± 2.01,P ＜0.05) but a higher urination symptoms score than the latter after medication (7.16 ± 1.04 vs 5.68 ± 1.34,P ＜ 0.05).At 4 weeks after drug withdrawal,the experimental group also showed significantly lower scores of the pain symptom (7.23 ± 1.03),QoL (6.58 ± 0.87) and total NIH-CPSI (22.18 ± 2.03) than the baseline (all P ＜ 0.05) and those in the control group (14.14 ± 0.98,8.12 ± 0.72 and 26.89 ± 1.67) (all P ＜ 0.05).Apart from dizziness in 2 of the patients,who gave up medication halfway,no other obvious adverse reactions were observed during the experiment.Conclusion:Lamiophlomis Rotata Capsule deserves to be recommended for the treatment of type Ⅲ B prostatitis for its safety and effectiveness in reducing the pain and improving the life quality of the patients.
Keywords：Lamiophlomis Rotata Capsuleprostatitispaintreatment
Publication Date：2017-12-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1107-1110 )