Topical application of clobetasol propionate cream in the treatment of phimosis in prepubertal children: A report of 237cases
WEN Yan-lin
WANG An-guo
ZHANG Zong-ping
WU Ji
JIANG Tao
Abstract：Objective:To investigate the clinical effect of 0.02％ clobetasol propionate cream (CPC) on phimosis in prepubertal children.Methods:We retrospectively analyzed the clinical data about 237 prepubertal children with phimosis present at the Outpatient Department from June 2012 to December 2015.The patients were aged 2-14 (mean 8.6) years,all treated by topical application of 0.02％ CPC to the narrowed opening and adhered part of the foreskin twice a day,in the morning and evening respectively.At the time of CPC application,the foreskin was slightly retracted.We evaluated the therapeutic effect every week from the end of the first week of treatment.Results:Totally,233 of the patients completed the 8-week treatment,of whom 181 (77.68％) showed full retraction of the foreskin,28 (12.01％) experienced improvement (disappearance of the phimotic ring),and 24 (10.30％) failed to respond,with a total effectiveness rate of 89.70％.No significant local or systemic adverse reactions were observed during the treatment.Conclusion:Topical application of 0.02％ Clobetasol Propionate Cream is a safe,effective,painless,and inexpensive option for the treatment of phimosis in prepubertal chilodren.
Keywords：clobetasol propionate creamsteroidphimosischild
Publication Date：2017-07-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 635-638 )