Genetic genes associated with oligospermia, asthenospermia and teratospermia: Advances in studies
GAO Ke
WANG Zhi-qiang
LIU Xing-chen
Abstract：Approximately 2,300 genes are found to be associated with spermiogenesis and their expressions play important roles in the regulation of spermiogenesis.In recent years,more and more attention has been focused on the studies of the genes associated with oligospermia,asthenospermia and teratospermia and their molecular mechanisms.Some genes,such as GSTM1,DNMT3L,and CYP1A1,have been shown to be potentially associated with oligospermia;some,such as CATSPER1,CRISP2,SEPT4,TCTE3,TEKT4,and DNAH1,with asthenospermia;and still others,such as DPY19L2 and AURKC,with teratospermia.These findings have provided a molecular basis for the studies of the pathogenesis of oligospermia,asthenospermia and teratospermia,as well as a new approach to the exploration of new diagnostic and therapeutic techniques.
Keywords：oligospermiaasthenospermiateratozoospermiagene
Publication Date：2017-04-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 367-371 )