Partial ejaculatory duct obstruction induces hemospermia syndrome in the rat model
XIAO Fei
BAI Wen-jun
WANG Xiao-feng
Abstract：Objective:To investigate the pathogenesis of hematospermia syndrome using the rat model of hemospermia induced by partial ejaculatory duct obstruction. Methods:Fifty male rats were divided into Groups A (n = 20) and B (n = 30),the former subjected to incomplete ligation of the right ejaculatory duct,while the latter open-close sham operation. Electro-stimulation was performed for ejaculation induction one week after the operation. Those that developed hematospermia in Croup A were chosen as Group A1,while those with normal ejaculation in Group B included in Group B1. The semen indexes and seminal vesicle pressure were compared between Groups Al and Bl. Results:Compared with Group Bl,Group Al showed significantly decreased semen volume (P < 0.01),lower sperm motility (P < 0.01) and higher seminal vesicle pressure (P < 0.01) ,but no statistically significant differences were observed in the WBC count and sperm density in the semen between the two groups ( P > 0.05 ). Conclusion:. Hemospermia syndrome can be induced by partial ejaculatory duct obstruction,with changes of semen indexes,and it is closely correlated with high seminal vesicle pressure.
Keywords：rat modelhematospermiapathogenesispartial ejaculatory duct obstructionseminal vesicle pressure
Publication Date：2010-03-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 240-243 )