MTHFR gene polymorphism and male infertility
LI Shan-shan
LI Jian
Abstract：Unexplained male infertility is mostly due to sperm-related gene mutations in the spermatogenie process.Methylenetetrabydrofolate reduetase(MTHFR)plays an important role in the process of DNA,RNA and protein metabolism,and is closely related with spormatogenesis.Researchers have found more than 20 single nueleotide polymorphisms(SNP)of the MTHFR gene.The polymorphisms of MTHFRC677T and A1298C my have a close relationship with male infertility.But the correlation between MTHFRG1793 and male infertility needs to be further studied.
Keywords：methylenetetrahydrofolate reductasemale infertilitysingle nueleotide polymorphism
Publication Date：2010-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 60-64 )