Increased Level of Prostate-Specific Antigen: A Diagnostic Marker of Hypterandrogenism Women
WANG Guo-hong
XU Rui-ji
ZHANG Zhong-shu
Abstract：Objective: To determine whether the increased level of serum prostate-specific antigen (PSA) could be used as a diagnostic marker of hyperandrogenism in women. Methods : Forty-five female patients with hypterandrogenism and 50 healthy control women were detected for the levels of serum PSA, testosterone (T), sex hormone binding globulin (SHBG) and dehydruepiandrosterone sulfate (DHEA-S). The results were statistically analyzed. Results: The level of serum PSA was found to be significantly higher in the hyperandrogenism patients than in the healthy controls (9.72±1.39 pg/ml vs 3.56±0.44 pg/ml, P < 0.01), and it showed a weak positive correlation with T (r=0.226, P < 0.05) and DHEA-S (r =0.255, P < 0.05), and a weak negative correlation with SHBG (r =-0,228, P < 0.05). Conclusion : The increased level of PSA could be used as a diagnostic marker of hyporandrogenism in females.
Keywords：prostate-specific antigenhyperandrogenismfemale
Publication Date：2009-10-26
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1028-1030 )