Diagnosis and Treatment of Ovotesticular Disorders of Sex Development in Children
LU Liang-sheng
RUAN Shuang-sui
BI Yun-li
LU Yi-qun
WANG Xiang
GE Lin-juan
XIAO Xian-min
Abstract：Objective:To investigate the diagnosis and treatment of ovotesticular disorders of sex development(DSD)in children. Methods:We reviewed the clinical data of 9 cases of ovotestieular DSD admitted in our department from 1988 to 2007. Results:The patients ranged in age from 9 months to 9 years,7 raised as males and 2 as females.As for the karyotype,4 cases were 46,XX,2 were 46,XX/46,XY,1 was 46,XY,and the other 2 had no karyotype data.All of them presented with obscure external genitalia:pedneal or penoscrotal hypospadias with or without cryptorchidism in males and hypertrophy of the clitoris in females.They were diagnosed with ovotestieular DSD by gonad biopsy and underwent genitoplasty.Conclusion:The gender assignment of the ovotesticular DSD patient Was chiefly based on the development of external genitalia,dominant gonad,karyotype and the parents will.Laparoseopic technology is recommended in gonad biopsy and orchiopexy during the treatment of ovotesticular DSD.
Keywords：ovotesficular disorder of sex developmentdiagnosistreatmentlaparoscopy
Publication Date：2009-07-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 628-631 )