Relationship between multimodal CT imaging and neurological function in elderly patients with acute ischemic stroke and predictive efficacy for stroke recurrence events
ZHANG Tao
LI Yuxin
ZHONG Zheng
HUANG Wei
Abstract：Objective To analyze the relationship between multimodal CT imaging and neurological function in elderly patients with acute ischemic stroke(AIS)and its predictive efficacy for stroke recurrence events.Methods A total of 160 elderly AIS patients admitted in our hospital from January 2021 to December 2023 were retrospectively recruited,and based on the occurrence of stroke recurrence events or not,they were divided into a recurrence group(28 cases)and a non-recurrence group(132 cases).General clinical data were collected in all the patients.ROC curve was plotted to evaluate the efficacy of the parameters from multimodal CT imaging and the National Institutes of Health Stroke Scale(NIHSS)score in predicting stroke recurrence.Results The recurrence group had significantly higher uric acid and IL-6 levels,increased NIHSS score,longer mean transit time(MTT)and time to peak(TTP),and obviously lower cerebral blood volume(CBV)and cerebral blood flow(CBF)as well as decreased ratio of endovascular intervention when compared to the non-recurrence group(P<0.05,P<0.01).There were a statistically significant difference in the severity of cerebral infarction and intracranial vascular stenosis between the two groups(P<0.05,P<0.01).The MTT and TTP were positively correlated with the NIHSS score(r=0.671,r=0.704,P<0.05),while the CBV and CBF were negatively correlated with the NIHSS score(r=-0.546,r=-0.667,P<0.05).Multivariate logistic regression analysis indicated that NIHSS score,MTT,TTP,CBV,CBF,and severity of intracranial large vessel stenosis were independent influencing factors for stroke recurrence events(P<0.05,P<0.01).ROC curve analysis showed that the AUC values of MTT,TTP,CBV,and CBF were significantly lower than that of their combined detection,and the AUC values of multimodal CT imaging parameters and NIHSS score were notably lower than that of theire combined detection(P<0.01).Conclusion The parameters of multimodal CT imaging are closely associated with neurological function in elderly AIS patients.Combined detection of multimodal CT imaging parameters and NIHSS score has a high predictive value for stroke recurrence events.
Keywords：multimodal imagingstrokeneurologic manifestationsrecurrenceforecasting
Publication Date：2026-02-15
Online Publishing Date：2026-03-11(First online date of this platform, not the publication date of the document)
Pages：5( 143-147 )