Research Progress on the Correlation between High Altitude Hypoxia and Dyslipidemia
Abstract：In medicine, areas with an altitude of ≥2500 m are generally referred to as highlands. In China, regions with an altitude of more than 2500 m account for about one-third of the country's total land area, making it the country with the largest area of highlands in the world. Moreover, more than 140 million people live in highland areas, and approximately 40 million people enter high-altitude regions each year for various reasons. Therefore, nearly 180 million people in highland areas face the environment of high-altitude hypoxia. Studying the impact of high-altitude hypoxia on human health is of great significance [1]. Cardiovascular disease is the leading cause of death worldwide. Compared with plains, residents at high altitudes have a higher prevalence of cardiovascular diseases, but lower awareness, treatment, and control rates. Cardiovascular disease is the primary threat to the life and health of people in highland areas [2-3]. Dyslipidemia is one of the most serious risk factors for cardiovascular disease. Therefore, it is particularly important to explore the pathogenesis of high-altitude hypoxia and dyslipidemia. We review the research progress on the relationship between high-altitude hypoxia and dyslipidemia.
Keywords：DyslipidemiaHigh altitudeLipoprotein lipaseHigh altitude hypoxia
Publication Date：2025-12-15
Online Publishing Date：2025-12-29(First online date of this platform, not the publication date of the document)
Pages：4( 1748-1751 )