Research Progress on the Correlation between Sarcopenia Staging and Risk of Acute Cardiovascular Events in Elderly Patients with Coronary Heart Disease
Abstract：Atherosclerosis of the coronary arteries is the core pathological feature of coronary heart disease, and its incidence risk increases with age, mainly due to the decline in vascular wall elasticity and deterioration of endothelial function. Coronary heart disease-induced coronary artery stenosis further exacerbates myocardial ischemia and increases the risk of acute cardiovascular events [1-2]. Sarcopenia is a syndrome characterized by a progressive loss of skeletal muscle mass, reduced muscle strength, and impaired muscle function, which is also widely prevalent in the elderly population [3-4]. In recent years, the coexistence of sarcopenia in elderly patients with coronary heart disease has gradually attracted academic attention. These patients not only face myocardial ischemia and cardiac dysfunction caused by atherosclerosis of the coronary arteries, but the concurrent sarcopenia further complicates their condition [5-6]. Notably, there is a complex pathophysiological relationship between the severity of sarcopenia and the risk of acute cardiovascular events, but the specific mechanisms remain unclear. Therefore, in-depth exploration of the internal connection between sarcopenia staging and the risk of acute cardiovascular events in elderly patients with coronary heart disease is of great significance for early identification of high-risk groups, development of precise and effective interventions, and optimization of patient outcomes. This review aims to comprehensively summarize and integrate research progress in this field, providing a scientific basis for clinical practice and pointing out new ideas and directions for future research.
Keywords：Coronary Heart DiseaseSarcopenia StagingClinical ManagementAcute Cardiovascular Events
Publication Date：2025-12-15
Online Publishing Date：2025-12-29(First online date of this platform, not the publication date of the document)
Pages：3( 1745-1747 )