Research Progress on the Interaction between Astrocytes and Microglia in the Pathogenesis of Parkinson's Disease Mediated by Neuroinflammation
Abstract：Parkinson's disease is a neurodegenerative disorder that increases in incidence with age, affecting about 1% of people over 65 years old. Its neuropathological features include the loss of dopaminergic neurons in the substantia nigra-striatum, leading to a decrease in dopamine levels in the striatum [1]. It is estimated that by 2030, the number of Parkinson's disease cases worldwide will exceed 10 million. The exact causes of Parkinson's disease are still not fully understood, and various possible pathogenic mechanisms have been proposed, but the precise pathogenesis remains uncertain.
Keywords：Parkinson's diseaseAstrocytesInflammationMicroglia
Publication Date：2025-10-15
Online Publishing Date：2025-10-16(First online date of this platform, not the publication date of the document)
Pages：4( 1438-1441 )