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Role of Erythropoietin-Producing Hepatocellular Receptor (Eph) and Its Membrane-Bound Ligand Signaling Pathway in Vascular Homeostasis
Abstract:Vascular homeostasis refers to the optimal physiological balance state in which the vascular system maintains structural integrity and functional coordination. Prolonged stimulation by various pathogenic factors can disrupt this balance, leading to vascular homeostatic imbalance. Disruption and imbalance of vascular homeostasis, along with adverse remodeling, promote the occurrence and development of various cardiovascular and cerebrovascular diseases, playing a role in the development of diseases such as atherosclerosis, myocardial infarction, and ischemic stroke [1]. The erythropoietin-producing hepatocellular receptor (Eph) and its membrane-bound ligand (Ephrin) signaling pathway is a receptor tyrosine kinase signaling pathway.
Keywords:vesselcardiovascular diseasevascular homeostasiserythropoietin-producing hepatocellular receptor
Publication Date:2025-10-15
Online Publishing Date:2025-10-16(First online date of this platform, not the publication date of the document)
Pages:4( 1434-1437 )