Research Progress on Glial Cell-Mediated Neuroinflammation in the Pathogenesis of Alzheimer's Disease
Abstract：Alzheimer's disease (AD) is a neurodegenerative disease that mainly affects middle-aged and elderly patients, characterized by progressive cognitive dysfunction. The current consensus is that the deposition of beta-amyloid peptide (Aβ) triggers neurofibrillary tangles, synaptic loss, and cell death, leading to the occurrence and development of AD. In recent years, increasing evidence has shown that the neuroinflammatory process plays an important role in the progression of AD, and activated microglia and astrocytes are closely related to neuroinflammation [1].
Keywords：Glial cellsAlzheimer's diseaseCentral nervous system diseases
Publication Date：2025-08-15
Online Publishing Date：2025-08-21(First online date of this platform, not the publication date of the document)
Pages：4( 1129-1132 )