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Role of Hippo and Yes-associated protein signaling pathways in atherosclerosis and advances in drug research
Abstract:Atherosclerosis (atherosclerosis, AS) is a chronic vascular inflammatory disease involving multiple cells, and it is the main pathological basis for various cardiovascular and cerebrovascular events, such as hypertension, coronary heart disease, angina pectoris, heart failure, acute myocardial infarction, cerebral hemorrhage, and cerebral infarction [1]. Studies have shown that endothelial cell dysfunction, macrophage polarization, and vascular smooth muscle cell (vascular smooth muscle cell, VSMC) migration and proliferation can all promote the occurrence and development of AS [2].
Keywords:AtherosclerosisEndothelial cellsMacrophages
Publication Date:2025-06-15
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 812-815 )