Effect of real-time interworking emergency mode on prognosis of patients with acute ischemic stroke
Tan Yi
Yu Houming
Abstract：Objective To investigate the effect and risk factors of pre-hospital real-time interwork-ing emergency mode on early neurologic deterioration(END)in patients with acute ischemic stroke(AIS)after thrombolysis.Methods A total of 186 AIS patients admitted to our hospital from April 2022 to September 2023 were recruited and randomly divided into a study group(pre-hospital 120-stroke real-time interworking emergency mode)and a control group(conventional treatment).The study group adopted a real-time pre-hospital 120-stroke team coordination emergency response model,while the control group received the conventional model.The NIHSS score,modified Rankin scale(mRS)score,door-to-imaging time(DIT),onset-to-door time(ODT),and door-to-needle time(DNT)were compared between the two groups before and after treatment,and the risk factors of severe END after thrombolysis were analyzed with multivariate logistic regression.Results After treatment,the study group obtained significantly lower NIHSS and mRS scores and shorter DIT and DNT than the control group(P＜0.05,P＜0.01).Of the 186 AIS patients,40(21.51％)developed END and 146 did not.Advanced age,larger proportion of hy-pertension,and higher blood glucose at admission and white blood cell(WBC)count,and lower ratio receiving real-time emergency mode were observed in the END group and the non-END group(P＜0.01).Multivariate logistic regression analysis indicated that age,hypertension,blood glucose at admission and WBC count were independent risk factors for the occurrence of END after thrombolysis in AIS patients(OR=1.132,95％CI:1.017-1.258,P=0.023;OR=5.115,95％CI:1.573-16.626,P=0.007;OR=1.560,95％CI:1.255-1.941,P=0.000;OR=2.162,95％CI:1.496-3.124,P=0.000).Conclusion P re-hospital 120-stroke emergency mode can shorten the treatment time,improve nerve function,and reduce the risk of END after thrombolysis,which is affected by age,hypertension,blood glucose and WBC count.
Keywords：first aidstrokeneurologic manifestationsregression analysisrisk factors
Publication Date：2025-03-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 343-347 )