Advances in the Application of Gold Nanoparticles in Myocardial Tissue Engineering
Abstract：Cardiovascular diseases are a leading cause of death worldwide, causing millions of deaths each year [1-2]. Although traditional treatments such as drug therapy, interventional surgery, and heart transplantation have played an important role in controlling the disease and prolonging patients' survival, they still face limitations such as drug resistance, surgical risks, and the shortage of donor organs [3-4]. These challenges are particularly severe in the elderly population, as older patients often have more comorbidities and lower tolerance for surgery. In recent years, myocardial tissue engineering, as an emerging interdisciplinary field, has aimed to repair and reconstruct damaged myocardial tissue by integrating cell technology, biomaterials, and engineering techniques [5-6]. Gold nanoparticles, due to their excellent biocompatibility, biodegradability, conductivity, optical properties, and unique surface-enhanced Raman scattering effect, have shown great potential in myocardial tissue engineering [7-8]. These properties not only provide new possibilities for the repair and regeneration of myocardial tissue but also bring new hope for the treatment of patients with heart disease. This review comprehensively discusses the advances in the application of gold nanoparticles in myocardial tissue engineering and deeply analyzes their potential and value in the treatment of cardiovascular diseases.
Keywords：NanomaterialsMyocardiumTissue EngineeringDrug DeliveryMolecular ImagingRegeneration
Publication Date：2025-02-14
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 248-250 )