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Research Progress of Circular RNA in Atherosclerosis
Abstract:Atherosclerosis (atherosclerosis, AS) is a pathological change characterized by the formation of atherosclerotic plaques or fibrous plaques in the vascular intima. It mainly involves large and medium arteries, leading to thickening and hardening of the arterial wall, narrowing of the lumen, and decreased elasticity, causing ischemic changes in the corresponding organs. AS is the main histopathological basis for cardiovascular diseases such as coronary heart disease. When the plaque ruptures or erodes, it can form a thrombus, narrowing the blood vessel, impeding blood flow, and even leading to myocardial infarction. AS-related cardiovascular diseases are a multifactorial chronic non-communicable disease. Although significant progress has been made in treatment and primary prevention, it remains the leading cause of death worldwide [1].
Keywords:RNAcircularmicroRNAsatherosclerosisendothelial cells
Publication Date:2025-02-14
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 241-244 )