Safety and efficacy of remote ischemic conditioning for cerebral hemorrhage in the elderly
Lin Meng
Ding Jian
Lian Xuegan
Yang Song
Abstract：Objective To evaluate the safety and efficacy of RIC in the treatment of elderly patients with ICH.Methods A prospective trial was conducted on 40 elderly patients with spontaneous ICH admitted to our hospital from January to August 2024.They were randomly assigned to a RIC group(20 cases,conventional treatment combined with RIC intervention)and a control group(20 cases,conventional treatment combined with sham intervention).Hematoma absorption,prog-nosis,and adverse reactions were compared between the two groups.Results The hematoma ab-sorption rate at 7 d after admission was(44.80±14.40)％in the RIC group,which was higher than that of the control group(38.50±20.80)％,though no statistical difference was seen be-tween the two groups(P＞0.05).There was no significant difference in the NIHSS score on the 7th day between the two groups(P＞0.05).At 30 d,the proportion of the patients with mRS ≤2 was 50.0％in the RIC group and 35.0％in the control group,but there was no obvious difference between them(P＞0.05).The proportions of patients with cuff marks and skin petechiae were no-tably higher in the RIC group than the control group(40.0％vs 0.0％,P＜0.01;45.0％vs 0.0％,P＜0.01),but no skin ecchymosis or serious adverse events were observed in both groups.Conclu-sion RIC treatment shows good safety and tolerability in treatment of spontaneous ICH in elder-ly patients.Although it has a potential trend towards promoting hematoma absorption and neuro-logic improvement,its short-term therapeutic effect is not significant.
Keywords：cerebral hemorrhagesafetyprognosisremote ischemic conditioning
Publication Date：2024-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1463-1466 )