Correlation of APCV sign with early neurological deterioration in patients with acute anterior circulation cerebral infarction
Tang Zhiqi
Zhang Min
Pan Changjie
Yun Wenwei
Abstract：Objective To investigate the relationship between APCV sign on SWI and END in pa-tients with acute anterior circulation cerebral infarction.Methods A retrospective study was con-ducted on 146 patients with acute anterior circulation cerebral infarction who were consecutively admitted in our hospital from May 2023 to March 2024.According to the results of SWI,they were divided into a negative APCV sign group(93 cases)and a positive APCV sign group(53 cases),and based on the progression of END or not within 3 d after admission,they were also assigned into a non-END group(97 cases)and an END group(49 cases).The general clinical data were compared between the negative and positive APCV sign groups and between the non-END and END groups.Multivariate logistic regression analysis was used to identify the risk factors for END and analyze the relationship between the occurrence of END and APCV sign in cerebral infarction.Results The positive APCV sign group had significantly larger proportions of hypertension and diabetes,higher glycosylated hemoglobin level and NIHSS score at admission,and elevated infarct volume than the negative APCV sign group(P＜0.01).Advanced age,higher ratios of hyperten-sion and diabetes,elevated NIHSS score,larger infarct volume and more APCV sign were ob-served in the END group than the non-END group(P＜0.05,P＜0.01).Multivariate logistic re-gression analysis showed that APCV sign was an independent risk factor for the occurrence of END in acute anterior circulation cerebral infarction after adjusting the variables,including age,hypertension,diabetes,N1HSS score,and infarct volume(OR=6.629,95％CI:1.799-24.428).Conclusion APCV sign is an independent risk factor for the occurrence of END in cerebral infarc-tion,and its appearance on the SWI sequence is an early marker in predicting the prognosis of cer-ebral infarction.
Keywords：brain infarctionasymmetrical prominent cortical veinsearly neurological deteriora-tionsusceptibility weighted imaging
Publication Date：2024-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1447-1451 )