Related factors for silent brain infarction in elderly patients with carotid artery stenosis after carotid endarterectomy
Yu Haijia
Zhang Yinsong
Li Shang
Xiang Yi
Zhang Mingzhe
Li Guangjie
Abstract：Objective To explore the risk factors for SBI after CEA in elderly patients with CS.Methods A total of 216 elderly CS patients undergoing CEA in our department from April 2020 to April 2023 were divided into SBI group(39 cases)and non-SBI group(177 cases)according to the occurrence of SBI in 30 d after surgery or not.The risk factors for SBI after CEA in elderly CS patients were screened out,and then a prediction model of SBI was constructed based on these risk factors.The prediction model was validated and its prediction efficacy was evaluated.Results Significantly larger proportions of severe CS,non-hyperechoic plaque and vulnerable carotid plaque,and higher levels of Hcy and TG were observed in the SBI group than the non-SBI group(P＜0.05).The severe carotid stenosis,non-hyperechoic plaque,vulnerable carotid artery plaque,Hey ≥13.81 μmol/L,and TG≥4.76 mmol/L were all risk factors for SBI after CEA in elderly CS patients(P＜0.05).The AUC value,sensitivity and specificity of the constructed model was 0.871(95％CI:0.715-0.939),94.50％and 76.30％respectively.Conclusion Severe carotid artery ste-nosis,non-hyperechoic plaque,vulnerable carotid artery plaque,Hey ≥13.81 μmol/L and TG ≥4.76 mmol/L are all risk factors for SBI after CEA.The prediction model based on the above risk factors has high predictive value for the occurrence of SBI after CEA in elderly CS patients.
Keywords：carotid stenosisbrain infarctionrisk factorscarotid endarterectomy
Publication Date：2024-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1443-1446 )