Clinical characteristics analysis of elderly patients with acute myocardial infarction complicated with ischemic stroke
Song Junxian
Cui Yuxia
Wang Meng
Chen Jiangtian
Chen Hong
Abstract：Objective To investigate the clinical characteristics of elderly patients with acute myo-cardial infarction(AMI)complicated with ischemic stroke and provide reference for the formula-tion of more precise prevention and treatment strategies.Methods A retrospective study was con-ducted on 439 consecutive AMI patients admitted to our department from January 2018 to Decem-ber 2019.They were divided into ischemic stroke group(n=55)and non-ischemic stroke group(n=384)based on having concomitant ischemic stroke or not.For the 114 patients who completed head CT angiography,they were assigned into ischemic stroke patients(n=27)and non-ischemic stroke patients(n=87).The clinical characteristics and intracranial arterial lesions were analyzed in the patients.Total score of intracranial artery calcification was used to evaluate the level of in-tracranial artery calcification and the degree of atherosclerosis.Results The ischemic stroke group had significantly larger proportions of concomitant hypertension,diabetes and renal dysfunction,pre-admission usage of aspirin/clopidogrel and statin,higher levels of glycosylated hemoglobin(HbA1c)and B-type brain natriuretic peptide,more 3-vessel lesions and elevated Gensini score,but decreased hemoglobin level,platelet count and estimated glomerular filtration rate when com-pared with the non-ischemic stroke patients(P＜0.05,P＜0.01).The proportions of intracranial artery calcification,severe calcification,intracranial artery carotid calcification,and intracranial artery stenosis ≥50％were obviously higher in the ischemic stroke patients than the non-ische-mic stroke patients(92.6％vs 78.2％,P=0.041;40.7％vs 21.8％,P=0.037;81.5％vs 62.1％,P=0.039;55.6％vs 35.6％,P=0.042).Binary logistic regression analysis showed that diabetes was an independent risk factor for ischemic stroke in the elderly AMI patients(OR=2.187,95％CI:1.205-3.970,P=0.010).Conclusion The elderly AMI patients complicated with ischemic stroke have more comorbidities,and severer disease condition,coronary artery disease and in-tracranial artery disease.In addition,coexistence of diabetes significantly increases the risk of is-chemic stroke in elderly AMI patients.
Keywords：myocardial infarctionstrokecoronary artery diseaseintracranial arterial diseases
Publication Date：2024-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1438-1442 )