Predictors of major adverse cardiovascular events after percutaneous coronary intervention

Qu Xiaolong; Yu Xudong; Ge Ruituo; Zhang Liyong; Zhang Shengzhang; Li Jie; Zhang Yuxiang

doi:10.3969/j.issn.1009-0126.2024.12.005

Abstract：Objective To explore the correlation of occurrence of major adverse cardiovascular events(MACE)with QRS-T angle,N-terminal pro-B-type natriuretic peptide(NT-proBNP)and fibrinogen(FIB)levels and platelet/lymphocyte ratio(PLR)in patients with acute myocardial in-farction(AMI)after percutaneous coronary intervention(PCI).Methods A retrospectively analy-sis was conducted on 98 AMI patients undergoing PCI in our department from May 2020 to June 2022.According to the occurrence of MACE or not,they were divided into MACE group(25 cases)and non-MACE group(73 cases).The general data and QRS-T angle,PLR,and Fib and NT-proBNP levels were compared between the two groups.Univariate logistic regression analysis and ROC curve analysis were used to analyze the influencing factors and predictive efficacy for MACE occurrence in AMI patients after PCI.Results Significantly larger QRS-T angle and PLR,and higher FIB and NT-proBNP levels were observed in the MACE group than the non-MACE group(P＜0.05,P＜0.01).Univariate logistic regression analysis showed that RS-T angle(OR=1.086,95％CI:1.043-1.131,P=0.000),PLR(OR=1.184,95％CI:1.102-1.272,P=0.000)and NT-proBNP level(OR=1.009,95％CI:1.004-1.014,P=0.000)were influencing factors for MACE occurrence in AMI patients after PCI.ROC curve analysis indicated that the AUC value of QRS-T angle,PLR and NT-proBNP level in predicting MACE after PCI in AMI patients was 0.822,0.870 and 0.907,with a sensitivity of 76.00％,76.00％and 84.00％,and a specificity of 72.60％,89.04％and 94.52％,respectively.Conclusion QRS-T angle,PLR and NT-proBNP are the influencing factors of MACE in AMI patients after PCI,and they have good predictive value.