Prediction of triglyceride-rich lipoprotein cholesterol for coronary artery lesions in elderly patients and evaluation of its predictive value
Qi Wei
Cong Hongliang
Abstract：Objective To investigate the correlation between triacylglycerol-rich lipoprotein choles-terol(TRL-C)level and the severity of coronary artery disease in elderly patients with coronary heart disease(CHD).Methods A total of 220 elderly CHD patients who underwent coronary an-giography in our hospital from January 1 to December 31,2020 were enrolled in this study.They were divided into mild coronary artery disease group(SYNTAX score 1-22,158 cases)and mod-erate to severe coronary artery disease group(SYNTAX score ≥23,62 cases).Logistic regression analysis and ROC curve analysis were used.Results Compared with the mild coronary artery dis-ease group,the moderate and severe coronary artery disease group had significantly lower albu-min,apolipoprotein(Apo)A and platelet count,while increased cTnT,NT-proBNP and TRL-C levels(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that TRL-C was a risk factor(OR=4.450,95％CI:1.572-12.599,P=0.005),while albumin was a protective factor for coronary artery disease(OR=0.880,95％CI:0.794-0.977,P=0.016).ROC curve analysis indi-cated that the AUC value of TRL-C for diagnosing moderate to severe coronary lesions was 0.655(95％CI:0.580-0.731).Conclusion TRL-C has a predictive value for the severity of coronary artery disease in elderly CHD patients,and has a predictive value for moderate to severe coronary artery disease.
Keywords：coronary artery diseaselipoproteinsforecastinglogistic modelstriglyceride-rich lipo-protein
Publication Date：2024-05-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 527-530 )