Imaging study of elderly first-ever ischemic stroke patients with asymptomatic coronary artery disease
Wang Chen
Du Xiangying
Li Yan
Qi Zhigang
Lu Jie
Abstract：Objective To explore imaging predictors in elderly patients with first-ever ischemic stroke combined with asymptomatic coronary artery disease(ACAD).Methods A total of 241 non-cardioembolic ischemic stroke patients within 14 d of symptom onset admitted to the neuro-logical department of our hospital from September 2019 to November 2021 were consecutively en-rolled.Based on the diagnosis,they were divided into an ACAD group(103 cases)and a non-ACAD group(138 cases).All patients underwent routine brain MRI and hybrid coronary and cer-vicocephalic CT angiography.Logistic regression analysis was used to identify factors influencing the presence of ACAD in these patients.Results The ACAD group had significantly larger ratios of males,smoking,silent brain infarcts(SBI,both single and multiple),positive stenosis in in-tracranial arteries,numbers of positive stenotic segments in intracranial and extracranial arteries,and total number of positive stenotic segments in head and neck arteries when compared with the non-ACAD group(P＜0.05,P＜0.01).Multivariate logistic regression analysis revealed that both single and multiple SBI were independent risk factors for ACAD(OR=4.474,95％CI:2.057-9.731,P=0.001;OR=8.071,95％CI:3.945-16.513,P=0.001).Conclusion SBI is an independ-ent predictive factor for ACAD in elderly patients with first-ever ischemic stroke,and it has better predictive value than cerebral white matter hyperintensities and intracranial/extracranial arterial stenosis for ACAD.
Keywords：strokecoronary diseaseangiographylogistic modelsforecasting
Publication Date：2023-12-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1264-1268 )