Relationship of left ventricular hypertrophy with cerebrovascular hemodynamic index and risk factors for ischemic stroke
Abstract：Objective To study the relationship of ECG-defined left ventricular hypertrophy (LVH) with cerebrovascular hemodynamic index (CVHI) and risk facrors for ischemic stroke.Methods A total of 1720 subjects with their age ≥65 years from a cerebrovascular disease cohort in Fengxian District of Shanghai City were divided into LVH group (n=101) and control group (n=1619).Relationship of LVH,CVHI and Framingham stroke profile (FSP) score with risk factors for ischemic stroke were analyzed.Results The CVHI score was 56.83±32.01 and 72.17± 29.52 respectively and the modified FSP score was 17.22±4.12 and 11.03±3.65 respectively in LVH group (P＜0.01).The cerebral blood velocity and volume were significantly lower while the peripheral resistance and pulse wave velocity were significantly higher in LVH group than in control group (P＜0.05).The relative risk of LVH,CVHI and FSP score in predicting ischemic stroke was 1.69 (95％CI:0.76-3.73),3.17 (95％CI:1.81-5.54) and 1.35 (95％CI:0.67-2.71) respectively.The CVHI score was an independent risk factor for ischemic stroke when the mutual influence of age,sex,and LVH,CVHI,FSP score on ischemic stroke was controlled.Conclusion LVH-related CVHI is an independent risk factor for ischemic stroke.
Keywords：hypertrophyleft ventricularhemodynamicsstrokeatherosclerosisvascular resistance
Publication Date：2017-01-01
Pages：4( 1295-1298 )