Application of diffusion tensor tractography in clinical rehabilitation of motor function in ischemic stroke patients
Abstract：Objective To analyze the damage of corticospinal tract in ischemic stroke patients with diffusion tensor tractography (DTT).Methods Thirty-seven ischemic stroke patients who underwent routine MRI scanning and DTT within 3 days after their disease onset.Their bilateral corticospinal tracts were plotted using MRI software.The patients were divided into grade Ⅰ group (n=10),grade Ⅱ group (n=12),and grade Ⅲ group (n=15) according to the severity of their corticospinal tract damage.Their general clinical data and NIHSS score were recrded.The patients were followed up for 6 months,during which the recovery of their motor function was assessed according to the Fugl-Meyer score (FMS) and the risk factors for FMS were analyzed.Results The NIHSS score on admission was significantly higher in grade Ⅲ group than in grade Ⅰ group and grade Ⅱ group (P＜0.05).The recovery of motor function was significantly better and the NIHSS score was significant higher in grade Ⅰ group than in grade Ⅲ group.The FMS was significantly higher in grade Ⅰ,Ⅱ andⅢ groups after 6 months of treatment than on admission (P＜0.01).Multivariate linear regression analysis showed that corticospinal tract damage,white matter lesion and NIHSS score on admission were the independent risk factors for the recovery of motor function(P＜0.01).Conclusion DTT can assess the damage of corticospinal tract in ischemic stroke patients.The damage of corticospinal tract is an important risk factor for the recovery of motor function in ischemic stroke patients.
Keywords：brain infarctiondiffusion magnetic resonance imagingpyramidal tractsrehabilitation
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1176-1179 )