Risk factors for left atrial thrombosis in elderly nonvalvular AF patients
Abstract：Objective To study the risk factors for left atrial thrombosis in elderly nonvalvular atrial fibrillation (NVAF) patients.Methods One hundred and sixteen elderly NVAF patients with transesophageal echocardiography-confirmed LA/LAA thrombosis served as a thrombus group and 116 NVAF patients without LA/LAA thrombosis served as a control group.The risk factors for LA/LAA thrombosis in two groups were analyzed by multivariate logistic regression analysis.Results The incidence of hypertension and ischemic stroke was significantly higher in thrombus group than in control group (65.52％ vs 51.72 ％,13.79％ vs 5.17％,P＜0.05).The prevalence of congestive heart failure was higher,the left atrial diameter (LAD) and left ventricular diastolic diameter were longer,the serum NT-proBNP level and CHA2DS2-VASc score were higher,the persistent/permanent atrial fibrillation (AF) ratio was greater in thrombus group than in control group (P＜0.01).Multivariate logistic regression analysis showed that persistent/permanent AF ratio,serum NT-proBNP level,CHA2DS2-VASc score and LAD were the independent risk factors for left atrial thrombosis in elderly NVAF patients (OR =5.721,95 ％ CI:2.069-15.820,P =0.001;OR=1.001,95％CI:1.000-1.002,P=0.002;OR=2.021,95％CI:1.316-3.103,P=0.001;OR=1.104,95％CI:1.002-1.216,P=0.046).Conclusion Persistent/permanent AF ratio,LAD,serum NT-proBNP level and CHA2DS2-VASc score are the risk factors for left atrial thrombosis in elderly NVAF patients.
Keywords：atrial fibrillationatrial appendagethrombosishypertensionstrokeheart failure
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1048-1051 )