Effect of early complete revascularization on outcome in acute ST-segment elevation myocardial infarction patients with multivessel lesions
Abstract：Objective To study the effect of drug-eluting stent (DES) implantation for early complete revascularization on the outcome in acute ST-segment elevation myocardial infarction (STEMI) patients with multivessel disease (MVD) after PCI.Methods Three hundred and eighteen acute STEMI patients with MVD admitted to our hospital from January 2007 and June 2009 were divided into control group (n=192) and treatment group (n=126).The patients in control group received culprit vessel only PCI and those in treatment group underwent DES for early complete revascularization.The incidence of MACE at the end of months 12 and 60 after PCI were compared between the two groups.Results The incidence of MACE and mortality were significantly lower in treatment group than in control group at the end of month 12 after PCI (7.9％ vs 16.1％,P=0.033;4.0％ vs 10.4％,P=0.037).The incidence of MACE was 31.3％ in treatment group and was 21.4％ in control group at the end of month 60 (P＞0.05).The all-cause mortality and cardiogenic mortality were significantly lower in treatment group than in control group at the end of month 60 after PCI (6.3％ vs 14.6％,P=0.023;4.8％ vs 12.0％,P=0.029).Conclusion DES implantation for early complete revascularization is safer than culprit vessel only PCI for early complete revascularization and can reduce the incidence of STEMI and all-cause mortality at the end of month 12 after PCI and the incidence of all-cause mortality and cardiogenic mortality at the end of month 60 after PCI in acute STEMI patients with MVD.
Keywords：myocardial infarctiondrug-eluting stentsshockcardiogenicprognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1043-1047 )