Risk factors for progressive perforating artery disease
Abstract：Objective To study the risk factors for progressive perforating artery disease (PAD).Methods One hundred and eighty-two AIS patients admitted to our hospital from August 2008 to December 2014 were divided into progressive PAD group (n=27) and non-progressive PAD group (n=155) according to the Chinese ischemic stroke subclassification and according to whether their condition was aggrevated.The risk factors for progressive PAD were analyzed by univariate logistic regression analysis.The cutoff of different risk factors was analyzed according to the ROC curve.Results Univariate logistic regression analysis showed that the incidence of hypertension,systolic blood pressure and diastolic blood pressure,serum levels of TC,LDL and D-dimer were significantly higher,the infarction size was significantly larger,the number of WBC was significantly greater in progressive PAD group than in non-progressive PAD group (P＜0.05,P＜0.01).The area under the ROC curve showed that infarction diameter ＞10.35 mm and D-dimer diameter ＞0.87 mg/L were the risk factors for progressive PAD in AIS patients (AUC=0.711,95％CI:0.606-0.817,P=0.009;AUC=0.639,95 ％CI:0.481-0.796,P=0.002).Conclusion Infarction diameter ＞10.35 mm and D-dimer diameter ＞0.87 mg/L are the risk factors for progressive PAD in AIS patients.
Keywords：brain infarctionleukocyte countcerebral arterial diseasesstrokeROC curve
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 961-964 )