Risk factor for chronic kidney disease in elderly essential hypertension patients
Abstract：Objective To analyze the risk factor for chronic kidney disease (CKD) in elderly essential hypertension (EH) patients.Methods A total of 977 EH patients were divided into elderly EH group (n=575) and non-elderly EH group (n=402) with 4610 subjects undergoing physical examination served as a control group in this study.The incidence of and risk factors for CKD were retrospectively analyzed.Results The detection rate of urinary protein and declined eGFR was higher in elderly EH group than in non-elderly EH group (28.5％ vs 11.4％,18.3％ vs 4.5％,P＜0.05).The detection rate of CKD was higher in elderly EH group than in non-elderly EH group and control group (33.7％ vs 12.4％,33.7％ vs 3.9％,P＜0.05,P＜0.01).With the increase of SBP every 20 mm Hg,the detection rate of CKD increased obviously (P＜0.05).The risk factor for CKD was DM followed by age,high serum uric acid level and SBP in elderly EH patients (OR=1.702,1.056,1.013,1.007,P＜0.01).Conclusion The detection rate of CKD is higher in elderly EH patients than in non-elderly EH patients.The incidence of CKD is related with blood glucose,serum uric acid level and blood pressure in elderly EH patients.
Keywords：hypertensionnephrosisproteinuriaglomerular filtration ratediabetes mellitushyperuricemia
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 948-951 )