Association between dyslipidemia and ischemic stroke in elderly population

doi:10.3969/j.issn.1009-0126.2017.09.002

Abstract：Objective To investgate dyslipidemia in community elderly population and analyze the association between its 4 components and ischemic stroke.Methods A total of 2080 patients were divided into ischemic stroke group (n=241) and non-ischemic stroke group (n=1839).Their gender,age,education level,smoking amd alcohol drinking history,BMI and physical exercise were analyzed by logistic regression analysis to display the effect of dyslipidemia and its components on ischemic stroke.Results The age was older,the smoking history and physical exercise time were longer in ischemic stroke group than in non-ischemic stroke group (P＜0.05,P＜0.01).The risk of ischemic stroke was 1.13-fold,1.51 fold and 1.78-fold higher respectively in patients with dyslipidemia than in those with ortholiposis,in patients with a high serum TG level than in those with ortholiposis,and in female elderly patients with a high serum TG level than in those with a normal serum TG level (95％CI:0.86-1.47,P=0.391;95％CI:1.15-2.00,P=0.004;95％CI:1.24-2.55,P=0.002).Multivariate logistic regression analysis showed that the risk of ischemic stroke was 1.57-fold higher in ＜80 years old female patients with a high serum TG level than in ≥80years old female patients with a high serum TG level (95％CI:1.10-2.23,P=0.012).Conclusion High serum TG increases the risk of ischemic stroke and is independent of the other 3 components of dyslipidemia in elderly population,especially in female and ＜80 years old population,health education and preventive intervention should thus be strengthened for such populations.