Application of standardized antiplatelet drugs in hospitalized elderly patients
Abstract：Objective To study the influencing factors for the application of antiplatelet drugs in hospitalized elderly patients.Methods A total of 2771 patients admitted to our hospital were divided into standard treatment group (n=2305) and control group (n=466).Their clinical data were retrospectively analyzed.Differences in their clinical data were analyzed by t test and multi-variate regression analysis respectively.Results Of the 2771 patients,standardized antiplatelet drugs were applied in 2305 (83.2％),unstandardized antiplatelet drugs were applied in 466 (16.8％).The compliance rate for antiplatelet drugs was higher in patients with smoking history,CHD,DM and was lower in those who were ≥75 years old,underwent PCI,diagnosed with peripheral atherosclerosis and anemia (OR=2.23;95 ％CI:1.75-2.83,P=0.001;OR=2.03,95 ％CI:1.60-2.58,P=0.000;OR=1.74,95％CI:1.38-2.20,P=0.000;OR=0.39,95％CI:0.32-0.49,P=0.000;OR=0.66,95％CI:0.50-0.87,P=0.000;OR=0.73,95％CI:0.58-0.92,P=0.000;OR=0.45,95％CI:0.32-0.64,P=0.004).Conclusion Of the patients included in this study,standardized antiplatelet drugs can be applied in 83.2％ and unstandardized antiplatelet drugs can be applied in 16.8％.Age,gastrointestinal disease,chronic kidney disease,interventional therapy and bleeding are the major influencing factors for the application of standardized anti-platelet drugs in elderly patients.
Keywords：platelet aggregation inhibitorscoronary diseasediabetes mellitusthromboembolism
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 812-815 )