Relationship between serum Hcy level and coronary artery stenosis in H type hypertension patients
Abstract：Objective To study the relationship between serum Hcy level and coronary artery stenosis in H type hypertension patients.Methods One hundred and eighteen essential hypertension (EH) patients with coronary artery disease were divided into experimental group (n=56) with their serum Hcy level ≥10 μmol/L and control group (n=62) with their serum Hcy level＜10 μmol/L.Their serum levels of Hcy,TC,TG,UA,and LDL-C were measured.The patients underwent coronary angiography.Their coronary artery stenosis and serum Hcy level were compared.Results The serum Hcy level was significantly higher in experimental group than in control group (13.2±2.9 μmol/L vs 6.1±3.2 μmol/L,P=0.000).The number of patients with mild stenosis was significantly less while that of patients with severe stenosis was significantly larger in experimental group than in control group (P=0.000).No significant difference was found in the number of patients with moderate stenosis between the two groups (P =0.448).Correlation analysis showed that serum Hcy level was positively related with Gensini score(r=0.71,95％CI:0.66-0.88,P=0.000).Coronary artery stenosis aggravated with the increasing serum Hcy level.Concision Serum Hcy level is closely related with coronary artery stenosis in H type hypertension patients.
Keywords：hypertensionhomocysteinecoronary stenosiscoronary diseasecoronary angiography
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 245-247 )