Acute lower respiratory infection increases the incidence of atrial fibrillation in very old hypertensive patients
Abstract：Objective To study the incidence of atrial fibrillation (AF) and its relative risk factors in very old hypertensive patients with acute lower respiratory tract infection.Methods Three hundred and forty-one ＞80 years old hypertensive patients admitted to our hospital from January 2011 to December 2013 were divided into infection group (n=192) and infection-free group (n=149).The incidence of AF in the patients on days 7,14,30 and 90 after admission was analyzed.The patients were further divided into new-onset AF group (n=11) and new-onset AF-free group (n=330).Results The incidence of AF was significantly higher in infection group than in infection-free group during the 90 days follow-up period (5.73％ vs 0％,P=0.003).The incidence of acute lower respiratory tract infection and its etiology were significantly different between newonset AF group and new-onset AF-free group (P＜0.05).Cox regression analysis showed that heart rate,infection type and LVEF on admission were the independent risk factors for new-onset AF during the 90 days follow-up period (HR =1.048,95 ％ CI:1.001-1.098,P =0.048;HR =113.815,95 ％CI:3.430-3777.011,P=0.008;HR=1.640,95％CI:1.058-2.541,P=0.027).Condusion Acute lower respiratory tract infection significantly increases the incidence of new-onset AF in very old hypertensive patients,its effective prevention and treatment can thus improve their poor outcome.
Keywords：respiratory tract infectionshypertensionatrial fibrillationage factors
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 232-235 )